Endocrine Abstracts

Introduction and aim: Interpretation of follicular neoplasia classification according to Bethesda system in thyroid fine needle aspiration biopsy is very different among pathologist. A number of definition including ‘follicular lesion’, ‘follicular proliferation’, ‘follicular lesion of undetermined significance’, and ‘follicular neoplasia’ were used in terminology. A clearly discrimination between nodular goitre, follicular adenoma, and ...

Introduction and aim: The most endocrinologists in routine practice are used to Bethesda classification for evaluation of thyroid nodule in fine needle aspiration biopsy (FNA). It is accepted that FNA biopsy is an accurate diagnostic and gold standard test. However, false-positive diagnosis may sometimes occur as a patient with a ‘malign’ lesion is found incorrectly rather than an actually benign lesion on histological examination. Hashimoto’s thyroiditis probab...

Introduction: Neutrophil lymphocyte rate (NLO), which is obtained from peripheric blood and used as mathematical rates of lymphocyte numbers, is accepted as available and practical indicator of systemic inflammation existence. We aimed to search NLO between Hashimoto’s thyroids patients who have autoimmune thyroid and also include an aetiopathogenesis auto-inflammatory process, and healthy control group with this study.Method: 59 patients who have b...

Adequacy of thyroid fine-needle aspiration (FNA) is generally defined by the thyroid follicle cells, amount, and quality of colloid. Samples priorly should be evaluated for adequacy. A set of qualifying criteria are specified in Bethesda system to remove subjectivity from the adequacy assessment. Each sample prepared from a thyroid FNA should be monitored at least six follicles cell groups containing at least ten cells. In addition to these criteria of assessing the adequacy, ...

Fine-needle aspiration biopsies (FNAB), adequate for examination, reported as benign re-evaluated with histopathological samples. 61 patients, 52 females and nine males re-evaluated. 41 of them reported as benign. 20 of the patients, seven females and three males reported as papillary carcinoma. Six of the papillary carcinomas were single focus, two muiticentric, and 12 papillary microcarcinoma. Six of the eight patients malignant lobe was different from the lobe that FNA was ...

Introduction and aim: Fine-needle aspiration (FNA) biopsy has become widely accepted as a reliable method for diagnosis of malign thyroid nodule. In our study we aimed to review results of thyroid FNA biopsy to be performed by same endocrinologist and compared to their histopathological results after thyroidectomy.Materials and methods: This retrospective study was done at the department of pathology for a period of 2 years from 2012 to 2014. The 401 pat...

Introduction: The criteria defining the threshold size of adrenal incidentaloma (AI) are >1 cm diameter. However, data about AI ≤1 cm diameter is scant. The aim of this study is to evaluate function of adrenal masses ≤1 cm and to compare them with adrenal masses >1 cm as well as to understand the possible utility of determining salivary cortisol in diagnosis of SCS in patients with AI.Method: The study included 137 consecutive patient...

Introduction: Polycycstic ovary syndrome (PCOS) is an important disorder in women of reproductive age which is characterised with menstrual dysfunction, anovulation and hyperandrogenism. 5–10% of the female population affected by this syndrome. Nesfatin-1 is a new anorexigenic hormone which is expressed from several regions of hypothalamus and peripheral tissues. Nesfatin-1 is related with obesity, insulin resistance and appetite. We aimed to evaluated the nesfatin-1 leve...

Introduction: We aimed to determine changes in geriatric assessment of cases with acromegaly.Methods: 26 elderly cases with acromegaly (controlled/uncontrolled: 15/11, F/M: 17/9) were included. 20 age, gender and BMI matched cases without acromegaly composed control group (CG) (F/M: 10/10). Presence of concomitant diseases and educational level were not different between the groups. Cognitive functions were evaluated with Mini Mental State Exam (MMSE), a...

Background: Adrenocortical carcinoma (ACC) is a rare cancer that originates from the cortex of the adrenal gland. Although its exact etiology is not clear, it has been found to be associated with some hereditary cancer syndromes. Sometimes patients present with hormonal excess symptoms (virilization, Cushing’s syndrome) or local symptoms consistent with an abdominal mass. In ACC, computed tomography (CT) and magnetic resonance imaging (MRI) are preferred imaging modaliti...